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Overexpression of pituitary tumor transforming gene (PTTG) is associated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma

โœ Scribed by Zhang, Jinfeng; Yang, Yingnan; Chen, Lantao; Zheng, Dayong; Ma, Jianqun

Book ID
124146205
Publisher
Elsevier Science
Year
2014
Tongue
German
Weight
746 KB
Volume
116
Category
Article
ISSN
0065-1281

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The pituitary tumor transforming gene 1 (PTTG1) protein is cell-cycle regulated and is identified as a human securin that inhibits sister chromatid separation and is involved in transformation and tumorigenesis. PTTG1 has very low or undetectable expression in most normal human tissues, but it is ab