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Overexpression of Parathyroid Hormone-Related Protein Causes Hypercalcemia but Not Bone Metastases in a Murine Model of Mammary Tumorigenesis

✍ Scribed by John J. Wysolmerski; Pamela R. Dann; Edward Zelazny; Maureen E. Dunbar; Karl L. Insogna; Theresa A. Guise; Archibald S. Perkins

Book ID: 111487136
Publisher: American Society for Bone and Mineral Research
Year: 2002
Tongue: English
Weight: 383 KB
Volume: 17
Category: Article
ISSN: 0884-0431
DOI: 10.1359/jbmr.2002.17.7.1164

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✍ Tsujimura, Hideki; Nagamura, Fumitaka; Iseki, Tohru; Kanazawa, Shoichiro; Saisho 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 88 KB 👁 2 views

Elevated levels of parathyroid hormone-related protein (PTHrP) in hypercalcemic myeloma patients were demonstrated in recent reports, suggesting that PTHrP behaves as a humoral mediator of hypercalcemia in myeloma. Herein we describe a hypercalcemic myeloma patient with a high serum PTHrP level. Mor