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Overexpression of p27 in relation to p53 and clinicopathologic variables in node-positive breast cancer

✍ Scribed by A. Tsuchiya; G.-J. Zhang; Y. Endo; I. Nakamura; T. Watanabe; I. Kimijima; S. Takenoshita


Book ID
117667278
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
110 KB
Volume
35
Category
Article
ISSN
0959-8049

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## Background and objectives: P27kip1 (p27) plays an important role as a negative regulator of cell cycle-dependent kinase activity during progression of the cell cycle. the most important prognosticator of breast cancer is nodal status, and the aim of this study was to determine the prognostic imp