## Abstract Alteration of the __Fhit__ gene was investigated in pancreatic duct adenocarcinomas induced by __N__โnitrosobis(2โoxopropyl)amine (BOP) in Syrian golden hamsters. The animals received 70 mg/kg BOP, followed by repeated exposure to an augmentation pressure regimen consisting of a choline
Overexpression of Midkine in Pancreatic Duct Adenocarcinomas Induced byN-Nitrosobis(2-oxopropyl)amine in Hamsters and Their Cell Lines
โ Scribed by Tsutsumi, Masahiro ;Kadomatsu, Kenji ;Tsujiuchi, Toshifumi ;Sakitani, Hiroyuki ;Ikematsu, Shinya ;Kubozoe, Tadahiko ;Yoshimoto, Masatoshi ;Muramatsu, Takashi ;Sakuma, Sadatoshi ;Konishi, Yoichi
- Book ID
- 108581835
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2000
- Tongue
- English
- Weight
- 308 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0910-5050
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## Abstract Alterations of the __Rassf1a__ gene were investigated in pancreatic duct adenocarcinomas (PDAs) induced by Nโnitrosobis(2โoxopropyl)amine (BOP) in hamsters. Female Syrian golden hamsters received 70 mg/kg BOP, followed by repeated exposures to an augmentation pressure regimen consisting
## Abstract The modification effects of nimesulide, a cyclooxygenase (COX)โ2 inhibitor, administration during the postinitiation phase of pancreatic carcinogenesis were investigated in hamsters treated with __N__โnitrosobis(2โoxopropyl)amine (BOP). Male Syrian hamsters were given 4 weekly s.c. inje
## Abstract We have used the polymerase chain reaction and dideoxynucleotide sequencing to amplify and sequence exons 1 and 2 of the cโKiโ__ras__ protoโoncogene from the normal Syrian golden hamster. Similar methods were employed to screen for the presence of point mutations in the cโKiโ__ras__ onc