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OVEREXPRESSION OF MATRIX METALLOPROTEINASE-2 AND THE INHIBITOR TIMP2 IN LIVERS FROM PATIENTS WITH GASTROINTESTINAL ADENOCARCINOMAS AND NO DETECTABLE METASTASIS

✍ Scribed by MUSSO, Orlando; THERET, Nathalie; CAMPION, Jean-Pierre; TURLIN, Bruno; LOREAL, Olivier; L'HELGOUALCH, Annie; CLEMENT, Bruno


Book ID
122004791
Publisher
Portland Press
Year
1996
Tongue
English
Weight
184 KB
Volume
86
Category
Article
ISSN
0248-4900

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Overexpression of matrix metalloproteina
✍ Nathalie ThΓ©ret; Orlando Musso; Jean Pierre Campion; Bruno Turlin; Olivier LorΓ©a πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 293 KB πŸ‘ 2 views

Degradation of basement membranes is a key step in tumoral invasion, mainly mediated by matrix metalloproteinases (MMPs) and their inhibitors (TIMPs). Since the liver is a main target for metastases from gastrointestinal adenocarcinoma, we have investigated MMP2 and TIMP2 expression by RT-PCR, in si