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Overexpression of inducible nitric oxide synthase and accumulation of 8-OHdG in nasopharyngeal carcinoma

✍ Scribed by Y Segawa; Y Oda; H Yamamoto; H Uryu; H Shiratsuchi; N Hirakawa; K Tomita; T Yamamoto; S Oda; T Yamada; S Komune; M Tsuneyoshi


Book ID
108780471
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
712 KB
Volume
52
Category
Article
ISSN
0309-0167

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Lipopolysaccharide (LPS) or a combination of interleukin (IL)-lp and interferon (1FN)-y cause transcriptional induction of a calcium-independent nitric oxide synthase (NOS) in astrocytes and C6 glioma cells. LPS induction of NOS in C6 cells was evidenced by a small amount of nitrite accumulation as