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Overexpression of human α-synuclein causes dopamine neuron death in primary human mesencephalic culture

✍ Scribed by Wenbo Zhou; Jerome Schaack; W.Michael Zawada; Curt R. Freed


Book ID
113997761
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
534 KB
Volume
926
Category
Article
ISSN
0006-8993

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## Abstract Overexpression or mutation of α‐synuclein (α‐Syn), a protein associated with presynaptic vesicles, causes familial forms of Parkinson's disease in humans and is also associated with sporadic forms of the disease. We used in vivo microdialysis, tissue content analysis, behavioral assessm