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Overexpression of Heme Oxygenase-1 Is Neuroprotective in a Model of Permanent Middle Cerebral Artery Occlusion in Transgenic Mice

✍ Scribed by Nariman Panahian; Masako Yoshiura; Mahin D. Maines

Book ID
111178124
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
719 KB
Volume
72
Category
Article
ISSN
0022-3042

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Overexpression of Heme Oxygenase-1 Is Ne
Overexpression of Heme Oxygenase-1 Is Neuroprotective in a Model of Permanent Middle Cerebral Artery Occlusion in Transgenic Mice
✍ Nariman Panahian; Masako Yoshiura; Mahin D. Maines πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 719 KB

Abstract : Heme oxygenase‐1 (HO‐1, HSP32) is an early gene that is responsive to an array of pathological conditions including, but not limited to, hypoxia and cerebral ischemia. HO‐1 cleaves the heme molecule and produces carbon monoxide (CO) and biliverdin (an antioxidant) and is essential for iro