Overexpression of heat shock transcription factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel
✍ Scribed by Natalia Vydra,Agnieszka Toma,Magdalena Glowala-Kosinska…
- Book ID
- 126371188
- Publisher
- BioMed Central
- Year
- 2013
- Tongue
- English
- Weight
- 752 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1471-2407
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Activation of the heat-shock or stress response is generally considered a cytoprotective response to heat or other proteotoxic stresses. In mammalian cells, stressinduced transcription of heat-shock genes is regulated by heat-shock transcription factor 1 (HSF1). We now show that activation of the Fa
## Abstract Human brahma‐related gene 1(__Brg1__) is a subunit of the switching/sucrose non‐fermenting (SWI/SNF) chromatin‐remodeling complex and regulates transcription during cell growth and differentiation and has been found to be mutated in many types of human cancers. Mammalian heat shock fact