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Overexpression of hCLP46 enhances Notch activation and regulates cell proliferation in a cell type-dependent manner

✍ Scribed by Chu, Q.; Liu, L.; Wang, W.


Book ID
120532848
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
810 KB
Volume
46
Category
Article
ISSN
0960-7722

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## Abstract p63 belongs to a member of the tumor suppressor protein p53 family. Due to alternative promoter usage, two types of p63 proteins are produced. The Ξ”Np63 isoform lacks the N‐terminal transactivation domain and is thought to antagonize TAp63 and p53 in target gene regulation. Ξ”Np63 has be