## Abstract Estrogen plays a key role in the development and progression of breast cancer; hence, antiestrogens, such as tamoxifen, have a marked impact on the treatment and outcome of breast cancer patients. Estrogenβinduced growth requires continuous replenishment of energy, predominantly generat
Overexpression of glut-1 glucose transporter in human breast cancer an immunohistochemical study
β Scribed by Raya S. Brown; Richard L. Wahl
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 941 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
This study examines the expression of the cell-cell adhesion molecules E-cadherin and its associated proteins, the catenins and the matrix-cell adhesion molecules 1-and 2-integrins, in primary invasive breast carcinoma. Expression was assessed immunohistochemically on frozen sections by semi-quantit
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcription factor that is involved in tumour growth and metastasis by regulating genes involved in response to hypoxia. HIF-1alpha protein overexpression has been shown in a variety of human cancers, but only 2 studies have documented the prognost
Polyamine transport is strongly induced by insulin and estradiol (E,) in ZR-75-I human breast cancer cells. Because signal transduction mechanisms of insulin and interleukin-4 (IL-4) partly overlap, we have compared the ability of these agents as well as that of interleukin-I3 (lL-l3), a cytokine th
## Abstract We have reported that nordihydroguaiaretic acid (NDGA) inhibits the tyrosine kinase activities of the IGFβ1 receptor (IGFβ1R) and the HER2 receptor in breast cancer cells. Herein, we studied the effects of NDGA on the growth of estrogen receptor (ER) positive MCFβ7 cells engineered to o