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Overexpression of G Protein-Coupled Receptor Kinase-2 in Smooth Muscle Cells Reduces Neointimal Hyperplasia

✍ Scribed by Karsten Peppel; Lisheng Zhang; Tam T.T. Huynh; Xuewei Huang; Anne Jacobson; Leigh Brian; Sabrina T. Exum; Per-Otto Hagen; Neil J. Freedman


Book ID
115633487
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
366 KB
Volume
34
Category
Article
ISSN
0022-2828

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## Abstract Hepatocellular carcinoma (HCC) is one of the deadliest forms of human liver cancer and does not respond well to conventional therapies. Novel effective treatments are urgently in need. G‐protein‐coupled kinase 2 (GRK2) is unique serine/threonine kinase that involves in many signaling pa