Overexpression of FGF8B in advanced stage and high grade prostate cancer
โ Scribed by V. Gnanapragasam; M. Robinson; C. Robson; F. Hamdy; D. Neal; H. Leung
- Book ID
- 118644792
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 218 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1569-9056
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๐ SIMILAR VOLUMES
## Abstract Fibroblast growth factor 8 (FGFโ8) is expressed at an increased level in a high proportion of prostate cancers and it is associated with a poor prognosis of the disease. Our aim was to study the effects of FGFโ8b on proliferation of PCโ3 prostate cancer cells and growth of PCโ3 tumors,
The authors evaluated 440 men with clinically staged and untreated prostate cancer with a monoclonal prostate-specific antigen (PSA) assay. The serum PSA value correlated significantly with both the stage and grade of disease (P < 0.00005). The relationships between PSA and consecutive Stages A, B,