Overexpression of EMS1/cortactin in NIH3T3 fibroblasts causes increased cell motility and invasion in vitro
โ Scribed by Patel, Ankita S; Schechter, Gary L; Wasilenko, William J; Somers, Kenneth D
- Book ID
- 110061357
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 429 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Protein tyrosine phosphatases (PTPases) represent a family of enzymes which together with protein tyrosine kinases (PTKases) play a critical role in cell proliferation and are likely involved in neoplastic transformation. Results presented here indicate that PTPases may also be involved in mechanism
The HMG-CoA reductase inhibitor, lovastatin, blocks targeting of the Rho and Ras families of small GTPases to their active sites by inhibiting protein prenylation. Control NIH3T3 cells, and those overexpressing human cyclin E protein were treated with lovastatin for 24 h to determine the effects of
NIH/3T3 mouse embryo fibroblasts were transfected with the cDNA for manganese superoxide dismutase (MnSOD). Previous studies showed characteristic unique AE profiles in nonsynchronous populations of parental, control plasmidtransfected, and MnSOD-overexpressing NIH/3T3 cell lines. However, the prese