Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype

Myeloablative chemotherapy followed by a

Myeloablative chemotherapy followed by autologous stem cell infusion may overcome the adverse prognostic impact of FLT3 (foetal liver tyrosine kinase 3) mutations in patients with acute myeloid leukaemia and normal karyotype

✍ Salvatore Palmieri; Felicetto Ferrara; Franco Leoni; Stefania Ciolli; Filiberto 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB

## Abstract In this study, we analysed the prognostic relevance of foetal liver tyrosine kinase 3 (FLT3) mutations in 73 patients with acute myeloid leukaemia (AML) with normal karyotype, who survived induction and consolidation and received autologous stem cell transplantation (ASCT) after success