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Overexpression of c-erbB-2 protein in gastric cancer. Its correlation with long-term survival of patients

✍ Scribed by Shinya Uchino; Hitoshi Tsuda; Keiichi Maruyama; Taira Kinoshita; Mitsuru Sasako; Takao Saito; Michio Kobayashi; Setsuo Hirohashi


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
588 KB
Volume
72
Category
Article
ISSN
0008-543X

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## Abstract The __HER2__ oncogene, which encodes the tyrosine kinase receptor, is commonly overexpressed in several types of cancer. Treatment using a humanized monoclonal antibody bound to __HER2__ product is becoming standard therapy for advanced breast cancer. Overexpression occurs in approximat