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Overexpression of Bcl-xL Promotes Chemotherapy Resistance of Mammary Tumors in a Syngeneic Mouse Model

✍ Scribed by Rebecca Liu; Carmen Page; David R. Beidler; Max S. Wicha; Gabriel Núñez

Book ID
117022760
Publisher
American Society for Investigative Pathology
Year
1999
Tongue
English
Weight
241 KB
Volume
155
Category
Article
ISSN
0002-9440

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## Abstract During cancer therapy with DNA‐damaging drug‐agents, the development of secondary resistance to apoptosis can be observed. In the search for novel therapeutic approaches that can be used in these cases, we monitored chemotherapy‐induced apoptosis resistance in a syngenic mouse tumor mod