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Overexpression of bcl-2 protein and mRNA in lymphocytes of inflammatory synovial infiltrates in chronic rheumatic disease

✍ Scribed by C. Schorpp; M. Zdichavsky; B. Koch; A. Nickels; M. Pfreundschuh; A. Gause


Book ID
108408974
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
187 KB
Volume
56
Category
Article
ISSN
0165-2478

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## Abstract Signal transduction and apoptosis in B‐cell chronic lymphocytic leukemia (CLL) cells with a post‐germinal center (GC) phenotype were studied. Specific activation of the cells was induced by a combination of soluble anti‐CD40 monoclonal antibody and interleukin‐4 (CD40/IL‐4) and nonspeci