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Overexpression of APP stimulates basal and constitutive exocytosis in PC12 cells

✍ Scribed by Hye-Won Lee; Jeong Won Park; Enkh-Undraa Sandagsuren; Ki-Bae Kim; Jin-Ju Yoo; Sul-Hee Chung

Book ID
116770305
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
490 KB
Volume
436
Category
Article
ISSN
0304-3940

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## Abstract Depolarization‐induced vesicle exocytosis is a complex mechanism involving a number of proteins. In this process, synaptotagmins work as members of the Ca^2+^‐sensing system that triggers the fusion of the synaptic vesicle with the plasma membrane. Synaptotagmin IV (SytIV), an immediate