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Overexpression of Acid Sphingomyelinase Sensitizes Glioma Cells to Chemotherapy

✍ Scribed by Grammatikos, Georgios; Teichgräber, Volker; Carpinteiro, Alexander; Trarbach, Tanja; Weller, Michael; Hengge, Ulrich R.; Gulbins, Erich

Book ID: 120084579
Publisher: Mary Ann Liebert
Year: 2007
Tongue: English
Weight: 289 KB
Volume: 9
Category: Article
ISSN: 1523-0864
DOI: 10.1089/ars.2007.1673

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## Abstract The developing central nervous system (CNS) is particularly susceptible to ethanol toxicity. The loss of neurons underlies many of the behavioral deficits observed in fetal alcohol spectrum disorders (FASD). The mechanisms of ethanol‐induced neuronal loss, however, remain incompletely e