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Overexpression of a member of the pentraxin family (PTX3) in human soft tissue liposarcoma

✍ Scribed by F. Willeke; A. Assad; P. Findeisen; E. Schromm; R. Grobholz; B. von Gerstenbergk; A. Mantovani; S. Peri; H.H. Friess; S. Post; M. von Knebel Doeberitz; M.H.M. Schwarzbach

Book ID
116429075
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
322 KB
Volume
42
Category
Article
ISSN
0959-8049

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The prototypic tissue pentraxin PTX3, in
The prototypic tissue pentraxin PTX3, in contrast to the short pentraxin serum amyloid P, inhibits phagocytosis of late apoptotic neutrophils by macrophages
✍ AndrΓ© P. van Rossum; Fausto Fazzini; Pieter C. Limburg; Angelo A. Manfredi; Patr πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 345 KB

## Abstract ## Objective Phagocytosis of apoptotic cells can be facilitated by complement components and short pentraxins, such as serum amyloid P (SAP). In contrast, the long pentraxin PTX3 was shown to inhibit phagocytosis of apoptotic Jurkat cells by dendritic cells and to bind late apoptotic p