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Overexpressing cellular repressor of E1A-stimulated genes protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis by activation of PI3K/Akt

✍ Scribed by Jie Deng; Yaling Han; Chenhui Yan; XIaoxiang Tian; Jie Tao; Jian Kang; Shaohua Li

Publisher
Springer
Year
2009
Tongue
English
Weight
602 KB
Volume
15
Category
Article
ISSN
1360-8185

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## Abstract Cell therapy with bone marrow‐derived mesenchymal stem cells (MSCs) has been shown to have great promises in cardiac repair after myocardial infarction. However, poor viability of transplanted MSCs in the infracted heart has limited the therapeutic efficacy. Our previous studies have sh