Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor
โ Scribed by An, J; Chervin, A S; Nie, A; Ducoff, H S; Huang, Z
- Book ID
- 110071837
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 322 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Androgenโindependent prostate cancers express high levels of Bclโ2, and this overโexpression of Bclโ2 protects prostate cancer cells from undergoing apoptosis. Ursolic acid (UA) has demonstrated an antiโproliferative effect in various tumor types. The aim of this study is to evaluate th
## Abstract Squamous cell carcinoma of the larynx can be treated using radiotherapy or surgery, either alone or in combination. Radiotherapy is preferred for earlyโstage tumours, as it spares the larynx and therefore preserves speech and swallowing. Unfortunately, approximately 15% of tumours treat
Over-expression of bcl-2, a potent anti-apoptosis protein, is likely to be one of the genetic mechanisms through which human prostate cancer cells develop resistance to hormonal and other forms of therapy. To develop a therapeutic agent for hormone-resistant prostate cancer based on suppression of b