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Overcoming the Demons of Protecting Groups with Amphoteric Molecules

✍ Scribed by Andrei K. Yudin; Ryan Hili


Book ID
102004955
Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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Protection of amines with the 4-azidomet
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A new urethane type protective group for amines, the 4-azidomethylenoxybenzyloxycarbonyl (AZ) group is described. This group is cleaved under very mild reductive conditions.It can be cleaved in the presence of the Z and methyl ester groups. Independent removal of AZ and BOC groups, each in the prese