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Overcoming poor permeability – the role of prodrugs for oral drug delivery

✍ Scribed by Hans Maag

Book ID
119226508
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
349 KB
Volume
9
Category
Article
ISSN
1740-6749

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✍ Victor R. Guarino; Kwame Nti-Addae; Valentino J. Stella 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 316 KB

The objective of this Letter is both to report the permeability results of a linezolid-based sulfenamide prodrug in an MDCK cell model (enterocyte surrogate system) and to discuss the strategic implications of these results for considering sulfenamide prodrugs to enhance the oral delivery of weakly