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Overcoming neurite-inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix

✍ Scribed by Cua, Rowena C.; Lau, Lorraine W.; Keough, Michael B.; Midha, Rajiv; Apte, Suneel S.; Yong, V. Wee

Book ID
120256986
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
858 KB
Volume
61
Category
Article
ISSN
0894-1491

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## Abstract Reactive gliosis caused by post‐traumatic injury often results in marked expression of chondroitin sulfate proteoglycan (CSPG), which inhibits neurite outgrowth and regeneration. Methylprednisolone (MP), a synthetic glucocorticoid, has been shown to have neuroprotective and anti‐inflamm