Overall survival from breast cancer in Kerala, India, in relation to menstrual, reproductive, and clinical factors

✍ Scribed by M. Krishnan Nair; R. Sankaranarayanan; K. Sukumaran Nair; N. Sreedevi Amma; Cherian Varghese; G. Padmakumari; Thomas Cherian

• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 418 KB
• Volume: 71
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19930301)71:5<1791::aid-cncr2820710513>3.0.co;2-w

✦ Synopsis

Background. Breast cancer accounts for one-fourth of cancer cases seen in female patients in Kerala, India. Results of a retrospective analysis of breast cancer in Kerala are presented in this article.

Methods. Case records of 449 patients with breast carcinoma treated during 1983-1984 were reviewed. Survival analysis was done by the Kaplan-Meier product limit method. The survival curves were compared by the log-rank test. A forward stepwise procedure with the Cox proportional hazards regression analysis was performed to identify factors influencing survival.

Results. The overall 5-year survival rate was 40%. The 5-year survival rates were 85% for patients with TI, 63% for T2, 32% for T3, and 21% for T4 lesions. Those with NO disease had a 68% 5-year survival rate. The survival rates were 90% for patients with Stage I, 65% for Stage II,33% for Stage 111, and 6% for Stage IV disease. On multivariate analysis, the following factors were found