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Over-expression of α7 nicotinic acetylcholine receptor induces sustained ERK phosphorylation and N-cadherin expression in PC12 cells

✍ Scribed by Kimiaki Utsugisawa; Yuriko Nagane; Daiji Obara; Hideo Tohgi


Book ID
117385992
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
713 KB
Volume
106
Category
Article
ISSN
0169-328X

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## Abstract Mammalian secreted lymphocyte antigen‐6/urokinase‐type plasminogen activator receptor‐related peptide‐1 (SLURP‐1) is a positive allosteric ligand for α7 nicotinic acetylcholine (ACh) receptors (α7 nAChRs) that potentiates responses to ACh and elicits proapoptotic activity in human kerat