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Over-expression of miR375 reduces glucose-induced insulin secretion in Nit-1 cells

✍ Scribed by Hua-Qiang Xia; Yi Pan; Ju Peng; Guang-Xiu Lu


Publisher
Springer
Year
2010
Tongue
English
Weight
255 KB
Volume
38
Category
Article
ISSN
0301-4851

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## Abstract TRB3 (a mammalian homolog of __Drosophila__) is emerging as an important player in the regulation of insulin signaling. TRB3 can directly bind to Ser/Thr protein kinase Akt, the major downstream kinase of insulin signaling. Conversely, physical exercise has been linked to improved gluco