Over-expression of BMP4 and BMP5 in a child with axial skeletal malformations and heterotopic ossification: A new syndrome

FGFR1 over-expression in primary rhabdom

FGFR1 over-expression in primary rhabdomyosarcoma tumors is associated with hypomethylation of a 5′ CpG Island and abnormal expression of the AKT1, NOG, and BMP4 genes

✍ Myriam Goldstein; Isaac Meller; Avi Orr-Urtreger 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 409 KB 👁 1 views

## Abstract Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma likely results from abnormal proliferation and differentiation during skeletal myogenesis. Multiple genetic alterations are associated with the three RMS histopathological subtypes, embryonal, alveolar, and pleomorphi