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Ovariectomy and gonadal hormone treatment: effects on insulin-like growth factor-1 receptors in the rat brain

✍ Scribed by Nahid K. El-Bakri; Atiqul Islam; Isam Suliman; Urban Lindgren; Bengt Winblad; Abdu Adem


Book ID
116512005
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
238 KB
Volume
14
Category
Article
ISSN
1096-6374

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## Abstract ## Objective To determine the effects of chronic deficiency of growth hormone (GH) and insulin‐like growth factor 1 (IGF‐1) on osteoarthritis (OA) severity. ## Methods Thirty‐five rats were divided into 4 treatment groups at 4 weeks of age: 1 control group (normal GH/IGF‐1 levels [he