Outer Membrane Vesicles of Bacteria

✍ Scribed by S.N. Chatterjee, Keya Chaudhuri (auth.)

Publisher: Springer-Verlag Berlin Heidelberg
Year: 2012
Tongue: English
Leaves: 164
Series: SpringerBriefs in Microbiology
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study that discovered the mechanism of OMV formation by a pathogen, Vibrio cholerae, and proposed that the process represented a novel secretory activity of bacteria. Furthermore, the authors present clinical and laboratory data on the use of OMVs as immunogens, as effective and licensed vaccines against Neisseria meningitidis serogroup B infections and on the development of more effective vaccines against other human and animal pathogens including Vibrio cholerae. This volume thus bears witness to the emerging revolution in the field of vaccines against pathogens and closes with a discussion of open questions and future research on OMVs.

✦ Table of Contents

Front Matter....Pages i-ix
Discovery of the Outer Membrane Vesicles: Revisiting Contemporary Works....Pages 1-13
Gram-Negative Bacteria: The cell Membranes....Pages 15-34
Factors Affecting Production of Outer Membrane Vesicles....Pages 35-45
Outer Membrane Vesicles as Carriers of Biomaterials....Pages 47-64
Outer Membrane Vesicles and the Biofilm Formation....Pages 65-69
Outer Membrane Vesicles: Interaction with Prokaryotes and Eukaryotes....Pages 71-79
Biogenesis of Outer Membrane Vesicles....Pages 81-90
Release of Outer Membrane Vesicles: Is it a Novel Secretion Mechanism?....Pages 91-94
Outer Membrane Vesicles: Physiological Medical Applications....Pages 95-145
Concluding Notes....Pages 147-150
Back Matter....Pages 151-161

✦ Subjects

Medical Microbiology; Immunology; Bacteriology; Membrane Biology

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