Outcomes of Lung Transplantation in Patients with Scleroderma
β Scribed by Malek G. Massad; Charles R. Powell; Jacques Kpodonu; Cimenga Tshibaka; Ziad Hanhan; Norman J. Snow; Alexander S. Geha
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 98 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0364-2313
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D-penicillamine has been used to treat systemic sclerosis (scleroderma) for nearly two decades. Improvement in cutaneous fibrosis in patients treated with this drug has been documented in a number of uncontrolled studies (1). The effect of D-penicillamine on established visceral involvement due to s
## Abstract ## Objective Lung transplantation is a viable, lifeβsaving intervention for several primary pulmonary disorders complicated by severe lung dysfunction. This study was undertaken to evaluate whether patients with systemic sclerosis (scleroderma), a systemic autoimmune rheumatic disorder
## Abstract ## Objective To assess the impact of cyclophosphamide (CYC) on the healthβrelated quality of life (HRQOL) of patients with scleroderma after 12 months of treatment. ## Methods One hundred fiftyβeight subjects participated in the Scleroderma Lung Study, with 79 each randomized to CYC