Outcome of Unstable Angina in Patients with Diabetes Mellitus

✍ Scribed by Fava, S.; Azzopardi, J.; Agius-Muscat, H.

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 47 KB
• Volume: 14
• Category: Article
• ISSN: 0742-3071
• DOI: 10.1002/(sici)1096-9136(199703)14:3<209::aid-dia324>3.0.co;2-b

✦ Synopsis

and b Government of Malta

This prospective hospital-based, case-control study compares the outcome of unstable angina in non-insulin dependent diabetic patients and non-diabetic control subjects. One hundred and sixty-two diabetic patients and 162 non-diabetic control patients with unstable angina were entered into the study. The 3-month mortality was 8.6 % (95 % confidence interval, CI = 4.4-12.9 %) in diabetic patients and 2.5 % (CI = 0.1-4.9 %) in control patients (p = 0.014). The 1-year mortality was 16.7 % (CI = 10.9 %-22.4 %) in diabetic patients and 8.6 % (CI = 4.4 %-12.9 %) in non-diabetic patients (p = 0.029). Diabetic patients received beta-blockade and underwent coronary angiography and angioplasty less frequently than controls; the frequency of unstable angina, of acute myocardial infarction, and of coronary artery bypass grafting was similar in both groups at 1 year of follow-up. It is concluded that diabetic patients with unstable angina have a higher mortality than non-diabetic patients and that this difference is largely accounted for by early (first 3 months) mortality.

KEY WORDS Unstable angina Outcome Non-insulin-dependent diabetes mellitus years in males and 68.8 (± 8.1) years in females). Patients