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Outcome of patients treated surgically for lymph node metastases from cutaneous squamous cell carcinoma of the head and neck

✍ Scribed by Babak Givi; Peter E. Andersen; Brian S. Diggs; Mark K. Wax; Neil D. Gross

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
174 KB
Volume
33
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

Background

There is a paucity of outcomes data for patients with lymph node metastasis from cutaneous squamous cell carcinoma of head and neck (SCCHN).

Methods

Patients from a tertiary care center with cutaneous SCCHN metastatic to parotid and or cervical lymph nodes were identified. Data were abstracted and analyzed using COX multivariate analysis.

Results

Fifty‐one patients (47 men, and 4 women) with a median age of 73 years were identified. Eight patients (16%) had recurrent disease and 11 (22%) were immunosuppressed. Forty patients (71%) received adjuvant radiation therapy. Median overall survival was 23 months (range, 3–148 months). Recurrent disease was associated with higher risk of death (hazard ratio [HR], 2.7; 95% confidence interval [CI] 1.1–6.9) and radiation therapy with reduced risk (HR, 0.18; 95% CI, 0.06–0.54).

Conclusion

Lymph node metastases from cutaneous SCCHN is associated with poor survival. Β© 2011 Wiley Periodicals, Inc. Head Neck, 2011

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