Outcome in patients with early colorectal carcinoma

✍ Scribed by Dr. L. F. Moreira; H. Iwagaki; A. Hizuta; K. Sakagami; K. Orita

• Publisher: John Wiley and Sons
• Year: 1992
• Tongue: English
• Weight: 359 KB
• Volume: 79
• Category: Article
• ISSN: 0007-1323
• DOI: 10.1002/bjs.1800790522

✦ Synopsis

Outcome in patients w i t h early colorectal carcinoma

Twenty-four patients seen between 1978 and 1990 with early colorectal carcinoma were reviewed to determine the outcome of surgical treatment. The mean age was 62 (range 35-79) years; there were 16 men and eight women. The site of the tumour was the ascending colon in two patients, sigmoid colon in ten and rectum in 12. The polypoid and $at-elevated ulcerated (IIa + IIc) subtypes were detected in 14 and nine lesions respectively. Restorative colectomy was carried out in 19 patients, andjive required Miles ' operation. There were no postoperative complications or deaths at a mean follow-up of 71 (range 12-151) months. Neither recurrence nor distant metastasis was found during follow-up. There was a close relationship between the depth of submucosal invasion and presence of $at-elevated ulcerated subtype lesions with lymphatic injiltration. This association may play an important role in the mechanism of metastasis. Major surgical resection is probably required i f longer disease-free intervals and better cure rates are desired.