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Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy

โœ Scribed by Packer, Roger J.; Sutton, Leslie N.; Elterman, Roy; Lange, Beverly; Goldwein, Joel; Nicholson, H. Stacy; Mulne, Lynn; Boyett, James; D'Angio, Giulio; Wechsler-Jentzsch, Kaethe; Reaman, Gregory; Cohen, Bruce H.; Bruce, Derek A.; Rorke, Lucy B.; Molloy, Patricia; Ryan, Janise; LaFond, Deborah; Evans, Audrey E.; Schut, Luis


Book ID
120423109
Publisher
American Association of Neurological Surgeons
Year
1994
Tongue
English
Weight
292 KB
Volume
81
Category
Article
ISSN
1933-0693

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Central nervous system tumors of childho
โœ Ward, H. W. C. ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 311 KB

CCNU was used in the treatment of 18 patients with childhood tumors of the CNS. Severe bone-marrow toxicity was noted. The initial dose was 130 mg/m2 given every 6 weeks, but it was often necessary to reduce the dose and prolong the interval between doses. The toxicity appeared to be much the same w