## Abstract NaK‐ATPase is a plasma membrane enzyme that plays a critical role in eutherian blastocoel formation (cavitation) by pumping Na^+^ into the extracellular space enclosed by the trophectoderm. Previous experiments with the mouse had shown that the α (catalytic) subunit of the enzyme become
Ouabain sensitivity and expression of Na/K-ATPase α- and β-subunit isoform genes during bovine early development
✍ Scribed by Dean H. Betts; Daniel J. MacPhee; Gerald M. Kidder; Andrew J. Watson
- Book ID
- 111658898
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 326 KB
- Volume
- 46
- Category
- Article
- ISSN
- 1040-452X
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We have used isoform-specific antibodies against the Na+, K(+)-ATPase alpha (alpha 1, alpha 2 and alpha 3) and beta (beta 1 and beta 2) subunit isoforms in order to establish their specific localization in isolated bovine articular chondrocytes. Immunoblotting confirmed the presence of the alpha 1 a
## Abstract ## BACKGROUND The purpose of this study was to determine the clinical significance of Na,K‐ATPase α‐ and β‐subunit expression in a histopathologically well‐characterized group of patients representing a wide spectrum of tumor grades and disease stages with transitional cell carcinomas