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Ouabain modulates the toxic action of glutamate in dissociated cultures of rat cerebellar granule cells

โœ Scribed by E. V. Stel'mashuk; N. K. Isaev; N. A. Andreeva; I. V. Viktorov

Publisher
Springer US
Year
1996
Tongue
English
Weight
908 KB
Volume
122
Category
Article
ISSN
0007-4888

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Modulation of calcium entry and glutamat
Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin
โœ Carmen Vale; Amparo Alfonso; Cristina Suรฑol; Mercedes R. Vieytes; Luis M. Botana ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 800 KB

## Abstract A channel open on the membrane can be formed by palytoxin (PTX). Ten nanomolar PTX caused an irreversible increase in the cytosolic calcium concentration ([Ca^2+^]~c~), which was abolished in the absence of external calcium. The increase was eliminated by saxitoxin (STX) and nifedipine