Other relevant literature

• Book ID: 102224600
• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: English
• Weight: 229 KB
• Volume: 4
• Category: Article
• ISSN: 0741-0395
• DOI: 10.1002/gepi.1370040109

✦ Synopsis

Genetic analysis of the fragile-X mental retardation syndrome with two flanking polymorphic DNA markers: Linkage analysis was performed in 16 families segregating the fragile site at chromosome band Xq27. Two polymorphic DNA markers were mapped to either side of the fraXq27 locus at 12 and 10% recombination, and should be useful for prenatal diagnosis. Transmission of the disease was detected through phenotypically normal males, as predicted by segregation analysis: I.