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Osteoprotegerin (OPG) expression in breast tumours and bone metastases

✍ Scribed by C. Van Poznak; P. Ottewell; S. Cross; C. Hudis; R.E. Coleman; I. Holen

Book ID
116319570
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
57 KB
Volume
38
Category
Article
ISSN
8756-3282

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## Abstract Most breast cancer metastases in bone form osteolytic lesions, but the mechanisms of tumor‐induced bone resorption and destruction are not fully understood. Although it is well recognized that Wnt/β‐catenin signaling is important for breast cancer tumorigenesis, the role of this pathway