Osteoporosis in Parkinson's disease

✍ Scribed by Brian Wood; Richard Walker

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 133 KB
• Volume: 20
• Category: Article
• ISSN: 0885-3185
• DOI: 10.1002/mds.20643

✦ Synopsis

Abstract

There are few studies of osteoporosis in Parkinson's disease (PD). We assessed the prevalence of osteoporosis in a PD clinic cohort. All subjects with a confirmed diagnosis of PD attending a clinic were invited to participate. All consenting subjects had bone density measured by dual energy X‐ray absorptiometry scanning. Further data, including demography, disease duration, and disease severity, were collected. One hundred five subjects participated; median age was 75 (54–92) years. Fifty‐one (49%) patients were men. Of the men: median T score, −1.3 (range, −4.7 to 3.8); median Z score, 0.0 (−3.2 to 4.7); diagnostic categories: osteoporosis, 20%; osteopenia, 41%; normal, 39%. Of the women: median T score −2.7 (−4.7 to 1.4); median Z score, −0.25 (−2.6 to 4.2); diagnostic categories: osteoporosis, 63%; osteopenia, 28%; and normal, 9%. Whole sample: osteoporosis, 42%; osteopenia, 34%; and normal, 24%. There were associations between age, depression, disease duration, and osteoporosis but not with disease severity. Female gender was an independent predictor of osteoporosis. The prevalence of osteoporosis/osteopenia is considerable in PD patients but does not exceed that of other people of similar age. Osteoporosis/osteopenia was present in almost all women of this age group with PD. © 2005 Movement Disorder Society