Osteoporosis: A Clinical Casebook

✍ Scribed by Natalie E. Cusano (editor)

• Publisher: Springer
• Year: 2021
• Tongue: English
• Leaves: 202
• Edition: 1st ed. 2021
• Category: Library

✦ Synopsis

Comprised of clinical cases of patients with osteoporosis, this concise, practical casebook will provide clinicians with the best real-world strategies to properly diagnose and treat the various elements of the disorder they may encounter. It presents a detailed cross-section of patients across all age groups, with different etiologies of the disease and possible complications, to present sensible management scenarios to physicians treating patients with osteoporosis. The cases presented include considerations for screening and diagnosis, assessment tools, nutrition and lifestyle choices, medical treatments, specific populations including men, the elderly and athletes, and more.  
Pragmatic and reader-friendly, Osteoporosis: A Clinical Casebook is an excellent resource for primary care providers, endocrinologists, rheumatologists, and other clinicians caring for patients with this disease.

✦ Table of Contents

Preface
Contents
Contributors
Abbreviations
1: Challenges in Screening and Diagnosis of Osteoporosis
Case Presentation
Assessment and Diagnosis
Management
Outcome
References
2: Nutrition and Lifestyle Approaches to Optimize Skeletal Health
Case Presentation
Management
Nutrition
Lifestyle
Outcome
References
3: The Utility and Applicability of Risk Assessment Tools and Trabecular Bone Score
Case Presentation
Assessment and Diagnosis
Management
Outcome
References
4: Steroids, Aromatase Inhibitors, and Other Drugs Associated with Osteoporosis
Case Presentation
Management
Glucocorticoids
Aromatase Inhibitors and Other Endocrine Therapies in Breast Cancer
Clinical Practice Points and Open Questions Regarding AIs
Other Medications Associated with Osteoporosis
Outcome
References
5: Secondary Causes and Contributors to Osteoporosis
Case Presentation
Assessment and Diagnosis
Outcome
References
6: Osteoporosis in Premenopausal Women
Case Presentation
Assessment and Diagnosis
Management
Outcome
References
7: Osteoporosis in Men
Case
Assessment and Diagnosis
Management
Outcome
References
8: Osteoporosis in the Elderly
Case Presentation
Assessment and Diagnosis
Management
Outcome
References
9: Relative Energy Deficiency in Sport/Functional Hypothalamic Amenorrhea
Case Presentation
Assessment and Diagnosis
Management
Outcome
References
10: Chronic Kidney Disease – Mineral and Bone Disorder (CKD-MBD)
Case Presentation
Assessment and Diagnosis
Management
Hyperphosphatemia
Secondary Hyperparathyroidism
Chronic Metabolic Acidosis
Osteoporosis
Outcome
References
11: Antiresorptive Therapy for Osteoporosis
Case Presentation
Management
Bisphosphonates (BPs)
Denosumab
Hormone Replacement Therapy (HRT)
Selective Estrogen Receptor Modulators (SERMs)
Outcome
References
12: Adverse Effects of Antiresorptive Therapy
Case Presentation
Background
Risk Factors
Clinical Pearls
Case Presentation
Background
Risk Factors
Clinical Pearls
Case Presentation
Background
Risk Factors
Clinical Pearls
Case Presentation
Background
Risk Factors
Clinical Pearls
Case Presentation
Background
Risk Factors
Clinical Pearls
References
13: PTH and PTHrP Analogs
Case Presentation
Assessment and Diagnosis
Management
Outcome
References
14: Sclerostin Inhibition
Case Presentation
Assessment and Diagnosis
The Sclerostin-Wnt Signaling Pathway
Sclerosteosis and Von Buchem’s Disease
Management
Animal Models
Clinical Trials and Studies
Dynamics of Romosozumab on Bone Metabolism
Safety
Outcome
References
15: “Drug Holidays”: When and How?
Case Presentation
Assessment and Diagnosis
Management
What Is a Drug Holiday?
Which Drugs Have Evidence for a Drug Holiday?
Drugs with Evidence Supporting a Drug Holiday: Alendronate, Zoledronic Acid, and Risedronate
Drugs with Evidence Against a Drug Holiday: Calcitonin, Denosumab, Raloxifene, Estrogen, Teriparatide, Abaloparatide, and Romosozumab
Drugs with Inconclusive/Insufficient Evidence for a Drug Holiday: Ibandronate
Who Is the Right Candidate for a Drug Holiday?
How Do You Monitor and Manage the Patient During a Drug Holiday? When Should the Drug Holiday End?
What Are Alternatives to a Drug Holiday?
Outcome
References
16: Osteoporosis Treatment Success and Failure
Case Presentation
Assessment and Diagnosis
Management
Outcome
References
Index