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Osteogenic Differentiation of Mesenchymal Stem Cells on Pregenerated Extracellular Matrix Scaffolds in the Absence of Osteogenic Cell Culture Supplements

✍ Scribed by Thibault, Richard A.; Scott Baggett, L.; Mikos, Antonios G.; Kasper, F. Kurtis

Book ID: 126493756
Publisher: Mary Ann Liebert
Year: 2010
Tongue: English
Weight: 393 KB
Volume: 16
Category: Article
ISSN: 1937-3341
DOI: 10.1089/ten.tea.2009.0583

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## Abstract Human mesenchymal stem cells (hMSCs) are characterized by their abilities to differentiate into different lineages, including osteoblasts. Besides soluble factors, mechanical strain and extracellular matrix (ECM) proteins play important roles in osteogenic differentiation of hMSCs. Howe