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Osteogenesis imperfecta, pathogenesis and treatment

✍ Scribed by Ö. Ljunggren; A. Kindmark; C. Rubim; K. Lindahl

Book ID
116321556
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
50 KB
Volume
44
Category
Article
ISSN
8756-3282

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Osteogenesis imperfecta (OI) comprises a group of disorders principally affecting type I collagen which result in increased bone fragility. Children with severe OI suffer recurrent fractures, resulting in severe deformity and growth stunting in many cases, with loss of independent ambulation by the