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Osteogenesis imperfecta in childhood: Treatment strategies

✍ Scribed by Raoul H.H. Engelbert; Hans E.H. Pruijs; Frits A. Beemer; Paul J.M. Helders

Book ID: 117045553
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 770 KB
Volume: 79
Category: Article
ISSN: 1532-821X
DOI: 10.1016/s0003-9993(98)90426-9

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Osteogenesis imperfecta (OI) comprises a group of disorders principally affecting type I collagen which result in increased bone fragility. Children with severe OI suffer recurrent fractures, resulting in severe deformity and growth stunting in many cases, with loss of independent ambulation by the