Osteocytes subjected to pulsating fluid flow regulate osteoblast proliferation and differentiation
โ Scribed by Peter S. Vezeridis; Cornelis M. Semeins; Qian Chen; Jenneke Klein-Nulend
- Book ID
- 116293408
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 247 KB
- Volume
- 348
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Bone cells subjected to mechanical loading by fluid shear stress undergo significant architectural and biochemical changes. The models of shear stress used to analyze the effects of loading bone cells in vitro include both oscillatory and unidirectional fluid shear profiles. Although th
## Abstract Loss of function mutations of __Perk__ (eukaryotic translation initiation factor 2 alpha kinase 3) in humans and mice cause severe neonatal developmental defects, including diabetes, growth retardation and multiple skeletal dysplasias. Comprehensive analyses on bone tissue, at the cellu