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Osteoclast cell fusion: mechanisms and molecules

✍ Scribed by Masaru Ishii; Yukihiko Saeki


Book ID
106292039
Publisher
Springer
Year
2008
Tongue
English
Weight
441 KB
Volume
18
Category
Article
ISSN
1439-7595

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## Abstract Bone marrow macrophages fuse on the bone surface to form multinucleated osteoclasts that then organize to efficiently resorb bone. Many, if not all, of the stages of macrophage fusion involve cytoskeletal components that reorganize the cells. Recruitment may involve chemotactic response