Osteoblast response to titanium surface roughness and 1?,25-(OH)2D3 is mediated through the mitogen-activated protein kinase (MAPK) pathway

Prostaglandins mediate the effects of ti

Prostaglandins mediate the effects of titanium surface roughness on MG63 osteoblast-like cells and alter cell responsiveness to 1?,25-(OH)2D3

✍ Batzer, R. ;Liu, Y. ;Cochran, D. L. ;Szmuckler-Moncler, S. ;Dean, D. D. ;Boyan, 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB 👁 2 views

Surface roughness affects proliferation, differentiation (alkaline phosphatase and osteocalcin), local factor production [transforming growth factor (TGF␤) and prostaglandin E 2 (PGE 2 )], and response to 1,25-(OH) 2 D 3 (1,25) of MG63 osteoblast-like cells. In this study, we examined whether the ef