✦ LIBER ✦
Osmotic complications of low-molecular-weight dextran therapy in free flap surgery
✍ Scribed by Charles K. Hardin; William C. Kirk; William C. Pederson
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 318 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0738-1085
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✦ Synopsis
Abstract
Low‐molecular‐weight dextran is utilized by many microsurgeons after free tissue transfer for its beneficial effects on the microcirculation. While it is generally felt to have a low rate of complications, severe complications secondary to dextran's osmotic effects may occur. We report here on two cases in which therapy with low‐molecular‐weight dextran was strongly implicated as a causative factor in major complications. These cases and their background are reviewed. Guidelines for the safe administration of this agent in patients post free‐tissue transfer are discussed.